0.5%
Educational Objective:
Estimate a patient's risk of gout in relation to uric acid levels.
Key Point:
Uric acid levels can be elevated even in completely asymptomatic patients.
Explanation:
The annual incidence of gout in people with a uric acid level between 7.0 and 8.9 mg/dL (normal range, 3.0-6.5 mg/dL) is 0.5%. Although dietary counseling is certainly appropriate for people with asymptomatic hyperuricemia, drug therapy is generally reserved for those who have had 2 symptomatic gout attacks.
References:
Dalbeth N, Merriman TR, Stamp LK. Gout. Lancet. 2016;388(10055):2039-2052.
Goldman L, Schafer AI. Goldman-Cecil Medicine. 25th ed., 2015.